Safety Joe

Chemical Resistant Gloves: Which Chemicals Require Which Glove Material?

When working with hazardous chemicals, choosing the right chemical resistant gloves is critical. Not all gloves protect against the same substances. A glove that performs well against gasoline may fail completely against acetone.

Understanding chemical compatibility helps prevent burns, skin absorption, and long-term exposure risks.

Below is a practical compatibility guide showing specific industrial chemicals and the glove materials that act as effective barriers.


Chemical Compatibility Chart: Common Industrial Chemicals

 

Chemical Common Use Nitrile Neoprene PVC Butyl Latex
Sulfuric Acid Battery plants, water treatment Good Excellent Good Excellent Moderate
Hydrochloric Acid Metal cleaning Good Excellent Good Excellent Moderate
Sodium Hydroxide Refineries, manufacturing Good Good Excellent Good Moderate
Acetone Paint removal, labs Poor Poor Poor Excellent Poor
Toluene Adhesives, coatings Fair Fair Poor Excellent Poor
Xylene Printing, rubber Fair Good Poor Excellent Poor
Gasoline Automotive, oil & gas Excellent Good Fair Poor Poor
Diesel Fuel Fleet maintenance Excellent Good Fair Poor Poor
Methanol Fuel processing, labs Good Good Fair Excellent Fair
Organophosphate Pesticides Agriculture Good Good Good Excellent Moderate

Understanding Glove Materials

Nitrile Gloves


Nitrile offers excellent resistance to petroleum products, oils, greases, and many acids. It is commonly used in automotive, oil & gas, and industrial maintenance.

Best for:

  • Gasoline and diesel

  • Oils and lubricants

  • Many industrial chemicals

Avoid prolonged exposure to:

  • Strong ketones like acetone

  • Aromatic solvents


Neoprene Gloves


Neoprene provides balanced protection across acids, caustics, and peroxides. It performs well in chemical plants and sanitation environments.

Best for:

  • Acid handling

  • Cleaning chemicals

  • Water treatment operations


PVC Gloves

PVC gloves are strong against acids and caustics but are not ideal for strong organic solvents.

Best for:

  • Chemical splash protection

  • Petrochemical handling

  • Janitorial applications


Butyl Rubber Gloves

Butyl provides superior resistance to ketones, esters, and highly aggressive solvents. It offers the highest resistance to gas and vapor permeation.

Best for:

  • Acetone

  • MEK

  • Hazardous solvent applications

  • Laboratory environments


When You Should Wear Chemical Resistant Gloves

Chemical resistant gloves are required when:

  • Handling concentrated acids or caustics

  • Transferring fuels or petroleum solvents

  • Mixing industrial cleaners

  • Applying pesticides

  • Performing chemical drum handling

  • Working where splash or immersion is possible

If skin contact could result in burns, absorption, or toxicity, gloves are not optional.


Always Check Breakthrough Time

Compatibility depends on:

  • Chemical concentration

  • Temperature

  • Exposure duration

  • Glove thickness

Always review manufacturer permeation data before selecting gloves for high-risk environments.

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